Haemoglobinopathies
- GP's role
- Prevalence of haemoglobinopathies
- Investigations
- Investigations of carriers for haemoglobinopathies in general
- Figure 1: Global distribution of haemoglobin disorders, in terms of births or affected
infants per 1000 births (WHO) - FBE and ferritin
- Possible results
- Haemoglobinopathy testing
- interpretation of results
- Figure 2: Suggested protocol for targeted carrier testing of high risk populations...
- Table 1: Interpretation of haemoglobinopathy carrier testing results
- DNA testing
- Indications for DNA testing
- Prenatal diagnosis
- Referral
- Condition-specific information
- β-Thalassaemia
- Clinical features
- Genetics
- Prevalence
- Investigations
- For affected individuals
- For potential or identified carriers
- Management
- α-Thalassaemia
- Clinical features
- Genetics
- Prevalence
- Investigations
- For affected individuals
- For potential or identified carriers
- Management
- Sickle cell disease (also known as HbS disease)
- Clinical features
- Genetics
- Prevalence
- Investigations
- Management
- Other haemoglobinopathies caused by structural change
- Table 2: Examples of states causing clinically significant haemoglobinopathies
- Further information
- Bibliography
- Patient and family fact sheet
- Haemoglobinopathies (including thalassaemias)